Translational value

Leishmaniasis treatment is a challenge is many tropical countries, and the equal challenge is effective treatments and resistance cases.

In the present study authors explored the effect of Iodum 30cH in the experimental visceral Leishmaniasis. The study model included both the therapeutic as well as prophylactic treatment of BALB/c mice infected with Leishmania donovani and given Iodium 30c for 30 days. The other group of mice was infected but given amphotericin B or alcohol only (Control group). The CD4+ and CD8+ T cells, and the biochemical analysis were performed to check any toxicities.

Iodium-treated animals showed a significantly reduced parasite load in therapeutic group and also in prophylactic group (slight less than controls). Iodium 30c had significant impact in controlling parasite replication in experimental visceral leishmaniasis.

Original Study Ref: Jyoti Joshi et al. The Effect of Iodium 30c on Experimental Visceral Leishmaniasis. Homeopathy 2020 Nov;109(4):213-223. https://pubmed.ncbi.nlm.nih.gov/32823292/

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