Translational value
- Apis mellifica and Histaminum have long been used in allergic disorders based on their clear symptomatology.
- It was 37 years back when B. Poitevin, E. Davenas, and J. Benveniste conducted the in vitro experiment for basophil degranulations with Apis and Histaminum. The experiments were blinded, and the basophil degranulation induced by anti-IgE was significantly inhibited by Histaminum (5cH, 15cH, and 18cH) and Apis (9cH and 10cH).
- It was concluded that,
“The investigation of the clinical efficacy of high dilutions of histaminum and Apis mel should be envisaged in allergic diseases in parallel with in vitro and ex vivo biological assays.”
Original Study Ref: Poitevin B, Davenas E, Benveniste J. In vitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica. Br J Clin Pharmacol. 1988;25(4):439-444.
Download:
Creative to share
For LinkedIn Weekly updates, please subscribe at https://www.linkedin.com/newsletters/research-updates-homeopathy-7213046888818692096.
For archives or to subscribe to Research Updates, visit https://researchinhomeopathy.org/ejournal.
